Cheryl Ruth Hines (born September 21, 1965) [1] is an American actress and comedian. She is best known for playing the role of Larry David 's wife, Cheryl, on HBO 's Curb Your Enthusiasm, for which she has been nominated for two Emmy Awards. 290 Followers, 266 Following, 161 Posts - See Instagram photos and videos from Cheryl Hines (@cherylhines).