Frederick, MD Weather Daily 21 Today Hourly 10 Day Radar Radar Video Video Get advanced radar. Go Premium Frederick, MD As of 6:21 pm EDT 77° Sunny Day 78° • Night 52° Tropical Weather. Frederick, MD Hourly Weather | AccuWeather 3 AM 45° RealFeel® 44° 7% Partly cloudy Wind SW 5 mph Air Quality Excellent Wind Gusts 8 mph Humidity 77% Indoor Humidity 33% (Slightly Dry) Dew Point.