POTS is a subset of orthostatic intolerance that is associated with the presence of excessive tachycardia on standing. 1 The current diagnostic criteria for POTS is a heart rate increase of 30 beats per minute (bpm) or more, or over 120 bpm, within the first 10 minutes. We appreciate our sponsors! Dysautonomia International is a non-profit that seeks to improve the lives of individuals living with autonomic nervous system disorders through research, physician education, public awareness and patient empowerment programs.